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Ketamine
Effects
by Erowid
DURATION #
Caution :   Reactions and experiences may vary dramatically from person to person. [see below]
Ketamine Duration
Insufflated / Nasal
Total Duration
45 - 60 mins
Onset
5 - 15 mins
Coming Up
10 - 30 mins
Plateau
20 - 40 mins
Coming Down
30 - 60 mins
 
 
After Effects
1 - 3 hrs
Hangover / Day After
Possible
Ketamine Duration
IM
Total Duration
30 - 60 mins
Onset
1 - 5 mins
Coming Up
5 - 20 mins
Plateau
20 - 45 mins
Coming Down
20 - 60 mins
 
 
After Effects
2 - 4 hrs
Hangover / Day After
Possible
 
EFFECTS LIST #
POSITIVE
  • Pleasant mental and/or body high
  • Increase in energy
  • Euphoria
  • Sense of calm and serenity
  • Meaningful spiritual experiences
  • Enhanced sense of connection with the world (beings or objects)
NEUTRAL
    (may be experienced as positive, negative or neutral depending on circumstance)

  • Distortion or loss of sensory perceptions (common)
  • Open- and closed-eye visuals (common)
  • Dissociation of mind from body
  • Analgesia, numbness
  • Ataxia (loss of motor coordination)
  • Loss of time perception
  • Increase in heart rate
  • Slurred speech
  • Confusion, disorientation
  • Out-of-body experience
  • Shifts in perception of reality
  • "K-hole"; intense mind-body dissociation, out-of-body experiences, highly realistic visuals
NEGATIVE
    (negative side effects increase with higher doses and frequent use)

  • Risk of psychological dependency
  • Nasal discomfort upon insufflation
  • Discomfort, pain or numbness at injection site (with IM)
  • Severe confusion, disorganised thinking
  • Paranoia and egocentrism (with regular use)
  • Nausea, vomiting
  • Frightening or untimely distortion or loss of sensory perception
  • Susceptibility to accidents (from uncoordination and change in perception of body and time)
  • Severe dissociation, depersonalisation
  • Loss of consciousness
  • Depression of heart rate and respiration (risk increases with increased dose or when combined with depressants)
  • See Ketamine and Health for more information
DESCRIPTION #
The effects of sub-anesthetic doses of ketamine are generally reported to be pleasant, though if they are unexpectedly intense, they can be distressing. A well-known effect of ketamine at higher-range doses is the "K-hole", where the user is removed from reality and set adrift in an introspective dream-like world, often involving complete dissociation, immersive visuals and out-of-body experiences. At higher doses, the user can be incapacitated and unresponsive, or uncoordinated and erratic, appearing unwell to the uninitiated eye. Nausea and vomiting may also be present.

While ketamine is not known to be physically addictive, prolonged use could be tolerance-building as well as leading to psychological dependency.

CAUTION & DISCLAIMER #
Erowid's effects information is a summary of data gathered from users, research, and other resources. This information is intended to describe the range of effects people report experiencing. Effects may vary dramatically from one person to another or one experience to another based on a variety of factors such as body chemistry, age, gender, physical health, dose, form of material, etc.

REFERENCES #
  1. CESAR. Ketamine. University of Maryland Center for Substance Abuse Research. Accessed Oct 2007.
  2. Various Authors. Erowid Experience Vaults Ketamine Reports. Accessed Oct 2007.