Chemicals marked on Erowid by our Research Chemical Symbol should be considered experimental chemicals. Although some people are willing to ingest these chemicals for their effects, it is not reasonable to assume that these chemicals are in any way 'safe' to use recreationally. Although all psychoactive use involves risk, this class of chemicals has undergone virtually no human or animal toxicity studies and there is little to no data on possible long term problems, addiction potential, allergic reactions, or acute overdoses.

Publication of information by Erowid about human use of these chemicals is not intended to endorse their non-laboratory use. It is important to remember that reactions to psychoactives vary dramatically from person to person. Extrapolating anything from any single person's experience with a chemical is inappropriate and may result in dangerous and possibly fatal abreactions.

Some reports of use may include extremely glowing "wow"-type experiences. Reports of this nature should not be misunderstood to suggest that they are common or typical of those who ingest the substance, or that the effects will be pleasant or desirable.

People should consider carefully before choosing to use these substances.